| 1. | 2 . the effect of ak auto ab on keratinocyte was investigated
利用亲和色谱法从正常人混合血清中纯化了akautoah 。 |
| 2. | Studies in vivo suggest that ak auto ab can facilitate the recovering of psoriasis like lesion
Akautoah对银屑病动物模型皮炎的转归具有促进作用。 |
| 3. | Our studies indicate that ak auto ab has a inhibitory effect on the proliferation of cultured keratinocytes . 3
发现纯化的akautoah对体外培养的角质形成细胞的增殖具有抑制作用。 |
| 4. | 5 . clinical studies show that transfusion of immunoglobin enriched in ak auto ab can prompt the recover of psoriasis . 6
临床上给银屑病患者输注富含akautoah的免疫球蛋白能明显促进皮损的康复。 |
| 5. | Genetic engineering anti - keratin anyibody was synthesised on the basis of clinical therapeutic prospect of ak auto ab . 7
在发现akautoah具有一定临床应用前景的前提下，应用抗体库技术获得基因工程抗体。 |
| 6. | Anti - keratin autoantibody ( ak auto ab ) targeted keratin of different molecular weight has also been found to exist virtually in healthy individuals
Akautoah广泛存在于正常人体内，包括可分别结合不同分子量角蛋白的抗体。 |
| 7. | Generally , the overall researches can be summarized to the following phases : 1 . ak auto ab was purified from human pooled sera by affinity chromatography
我们实验室对akautoah进行了广泛深入的研究，主要研究分为以下几个阶段： 1 |
| 8. | During the course of investigating the inhibitory mechanism , it has been also implicated that ak auto ab play an important role in preventing progression of squamous cell carcinoma
在应用体外实验研究akautoah作用机制的同时， akautoah4第四军医大学硕士学位论文阻止鳞癌细胞发展的作用也同时被揭示。 |
| 9. | The following reseaches were carried out to investigate the biological roles . a reseach by hinter showed that igg ak auto ab opsonized insoluable aggregates of keratin intermediate filament ( kif )
Hinter等通过研究发现igg型akautoah对不溶性的角蛋白中间丝（ keratiintermediateilament ， kif ）凝集物具有调理吞噬作用。 |
| 10. | Another research revealed that ak auto ab accelerated the clearance of keratin body dropped into dermis by binding to them . so far , abandent and detailed researches of ak auto ab have been conducted in our lab
还有研究表明， akautoah常常包绕结合于进入真皮中的角蛋白小体伙eratinbody3kb卜从而有可能积极地参与了kb的清除过程。 |
